Affinity maturation is often a necessary step for the development of potent therapeutic molecules.Many different diversification strategies have been used for antibody affinity maturation, including error-prone PCR, chain shuffling, and targeted complementary-determining region (CDR) mutation.Although effective, they Fab Parts can negatively impact
BackgroundResidual HIV-1 replication among individuals under antiretroviral therapy (ART) relates to HIV micro-inflammation.ObjectivesTo determine the levels of residual HIV replication markers among distinct subgroups of antiretroviral-treated individuals.MethodsOne hundred sixteen patients were distributed into 5 treatment groups: first-line supp
Foreign direct investment (FDI) has not only been considered to be an important economic engine to promote economic growth in China, but also has played a pivotal role in the ecological environment.Empirically, it may exhibit two conflicting effects, namely, pollution haven effect and pollution halo effect.Hence, it is of great significance of re-e
Blind image deblurring is a well-known conundrum in the digital image processing field.To get a solid and pleasing deblurred result, reasonable statistical prior of the true image and the blur kernel is required.In this work, a novel and efficient blind image deblurring method which utilizes the Local Maximum Difference Prior (LMD) is presented.We
Nowadays, smart farming involves the integration of advanced technologies that incorporate low-cost robots to meet the required knowledge and maintain the health of plants in farming.Technologies like precision agriculture are also used to optimize resources based on the field condition.Internet of Green Things is also one of the technologies to in